Director : Jean-Yves Hogrel
Our principal objectives are :
- Develop tools and evaluation methods of neuromuscular function.
These tools and methods are necessary for the diagnosis of the disease and the follow-up of motor unit performances. This priority research orientation is justified by the need to improve the quantitative follow-up of patients, particularly for the evaluation of pharmacological, gene or cellular therapies.
- To implement protocols allowing to emphasize and to better understand the physiological mechanisms at the origin of the functional modifications observed.
These protocols could be exploited for therapeutic trials of neuromuscular diseases, but also in other situations such as surgery, ageing, hypokinesia or reconditioning.
Thanks to its maintenance, innovation and technology transfer activities, the Laboratory is examining the possibilities of valorisation and clinical transfer of new techniques and diagnostic and follow-up methods for neuromuscular pathologies.
The Laboratory is also working on the development of an Assurance/Quality referential
. To our knowledge, a laboratory accredited in the field of functional explorations in the clinical environment does not exist. Nevertheless, it will be essential to guarantee the quality of neuromuscular force measurements during multicentric protocols whilst being based on validated procedures.
By starting an Assurance/Quality approach, the Laboratory, aims to be the driving force behind a network of accredited centres.
Members of the team :
• Jean-Yves Hogrel, PhD, Biomedical Engineer, Laboratory director, AIM
• Isabelle Ledoux, Biomedical Engineer, AIM
• Valérie Decostre, Physical therapist, AIM
• Aurélie Canal, Physical therapist, AIM
• Benali Mohamed, Physical therapist, Généthon
The laboratory also welcomes many masters, engineer or DUT (technology institute diploma) students.
Contact: + 33 1 42 16 58 74
Update: July 2010